When you get the drum off, you may find that your drill has ruined the threads. As already said, you don't really need the screw, the drum, in use, is clamped securely by the wheel. But if you do want it, to ensure that the drum never moves and perhaps allows dirt to get between itself and the hub during wheel changes, which would be bad, just fit the drum in a different position, spot mark the hub with an exact size drill, probably 1/4", drill right through with a tapping size drill, 3/16" is about right, tap 1/4" UNF, and fit a new screw.