I have a leaded head, and this is how I run it.
I Use Shell V Power (cleaner, better quality fuel) with Valvemaster + (the one with the octane booster). This way, you've now got very high octane fuel and leaded additive.
I have personally got the timing set up for the V power and use the octane booster in Valvemaster + to keep it safe if for some reason I couldn't get higher octane fuel.
With this set up you can get better performance (because of the higher octane) and it's still safe for leaded heads. If you don't want to/can't use a high octane fuel for whatever reason, then leave your timing where it is to prevent any risk of pre-ignition (pinking).